ABSTRACT
Objective:
There are many heart-lung machines and oxygenators with different features. In terms of patient safety, the selection and suitability of oxygenators are important. In this study, the effects of oxygenators with different surface areas on oxygen delivery during cardiopulmonary bypass on patients undergoing open heart surgery and clinical outcomes were compared.
Materials and Methods:
This is a single-center, cross-sectional, retrospective survey based on patients who had an open heart operation at İstanbul Koşuyolu heart center between February 2019 and April 2019. Patients were divided into 4 different groups according to the type of oxygenator used during the operation. The pO2/FiO2 ratio was used to evaluate oxygen transfer.
Results:
Of the 120 patients included in the study, 89 were male (74.2%). The mean age of the patients was 60.09+11.13 years and the mean body surface area (kg/m2) was 1.89+0.14. No difference was observed between the groups in terms of the change in haematocrit level at the end of cardiopulmonary bypass (p=0.853). Postoperative lactate dehydrogenase levels increased when the duration of cross time and cardiopulmonary bypass was prolonged (p<0.001). However, no difference was observed between the groups (p=0.604). pO2/FiO2 ratio was found to be lower in group C oxygenators (p<0.001). Statistically significant differences were found between oxygenator groups in terms of warm-up time (p=0.047). No difference was observed between the groups in terms of postoperative cerebrovascular events (p=0.069).
Conclusion:
The choice of oxygenator appears to have a significant impact on clinical outcomes and patient health. Comparisons between oxygenator groups showed that there were significant differences in terms of oxygen transfer during the surgical process.
Keywords:
Cardiopulmonary bypass, oxygenator, cardiac surgery, oxygen transfer, hemolysis, cerebrovascular accident
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